Publications

@article{Tsokanos2021,

title = {The Efficacy of Manual Therapy in Patients with Knee Osteoarthritis: A Systematic Review},

author = {A Tsokanos and E Livieratou and E Billis and M Tsekoura and P Tatsios and E Tsepis and K Fousekis},

doi = {https://doi.org/10.3390/medicina57070696},

year  = {2021},

date = {2021-09-01},

journal = {Medicina},

volume = {57},

number = {7},

pages = {696},

abstract = {Background and objectives: 

Osteoarthritis (OA) is among the most common degenerative diseases that induce pain, stiffness and reduced functionality. Various physiotherapy techniques and methods have been used for the treatment of OA, including soft tissue techniques, therapeutic exercises, and manual techniques. The primary aim of this systemic review was to evaluate the short-and long-term efficacy of manual therapy (MT) in patients with knee OA in terms of decreasing pain and improving knee range of motion (ROM) and functionality. 

 

Materials and Methods: 

A computerised search on the PubMed, PEDro and CENTRAL databases was performed to identify controlled randomised clinical trials (RCTs) that focused on MT applications in patients with knee OA. The keywords used were ‘knee OA’, ‘knee arthritis’, ‘MT’, ‘mobilisation’, ‘ROM’ and ‘WOMAC’. Results: Six RCTs and randomised crossover studies met the inclusion criteria and were included in the final analysis. The available studies indicated that MT can induce a short-term reduction in pain and an increase in knee ROM and functionality in patients with knee OA. 

 

Conclusions: 

MT techniques can contribute positively to the treatment of patients with knee OA by reducing pain and increasing functionality. Further research is needed to strengthen these findings by comparing the efficacy of MT with those of other therapeutic techniques and methods, both in the short and long terms.},

keywords = {knee osteoarthritis, manual therapy, Mulligan technique},

pubstate = {published},

tppubtype = {article}

}

@article{Karanasios2021c,

title = {Clinical effectiveness of shockwave therapy in lateral elbow tendinopathy: systematic review and meta-analysis},

author = {S Karanasios and G K Tsamasiotis and K Michopoulos and V Sakellari and G Gioftsos},

doi = {doi: 10.1177/02692155211006860},

year  = {2021},

date = {2021-03-01},

urldate = {2021-03-01},

journal = {Clin Rehabil},

volume = {35},

number = {10},

pages = {1383-1398},

abstract = {Objective: 

To evaluate the effectiveness of extracorporeal shockwave therapy compared with other interventions on pain, grip strength and disability in patients with lateral elbow tendinopathy. 

 

Data Sources: 

MEDLINE, PubMed, CINAHL, EMBASE, PEDro, ScienceDirect, Cochrane Library and clinical trial registries. 

Review methods: 

 

We included randomized controlled trials assessing the effectiveness of extracorporeal shockwave therapy alone or as an additive intervention compared with sham or other interventions. Pain intensity, grip strength and elbow disability were used as primary outcome measures. We assessed methodological quality with the PEDro score and quality of evidence with the GRADE approach. 

 

Results: Twenty-seven studies with 1871 patients were finally included. Extracorporeal shockwave therapy reduced pain intensity at mid-term follow-up (standardized mean difference: −1.21, 95% confidence interval:−1.53, −0.89, P < 0.001) and improved grip strength at very short- (mean difference:3.92, 95% confidence interval: 0.91, 6.94, P = 0.01) and short-term follow-up (mean difference:4.87, 95% confidence interval:2.24, 7.50, P < 0.001) compared with sham treatment. However, no clinically significant results were found between comparators in all outcomes and follow-up times. Extracorporeal shockwave therapy presented clinically better compared to Laser in grip strength at short-term (mean difference:3.50, 95% confidence interval:2.40, 4.60, P < 0.001) and ultrasound in pain intensity at very-short-term follow-up (standardized mean difference: −1.54, 95% confidence interval: −2.60, −0.48, P = 0.005). 

 

Conclusion: 

Low to moderate certainty of evidence suggests that there are no clinical benefits of extracorporeal shockwave therapy compared to sham interventions or corticosteroid injections. Based on very-low and moderate certainty of evidence, extracorporeal shockwave therapy outperforms against Laser and ultrasound, respectively.},

keywords = {lateral epicondylitis, meta-analysis, shockwave therapy, tennis elbow},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Greek population’s perceptions of nonpharmacological interventions towards the first wave of COVID-19 pandemic mitigation: A regressionbased association analysis},

author = {E C Boutsikari and A Christakou and M Elpidoforou and I Kopsidas and N Nikolovienis and D Kardara and C C Boutsikari and C Triantafyllou},

url = {https://doi.org/10.18332/pne/141592},

doi = {10.18332/pne/141592},

issn = {1105-848X},

year  = {2021},

date = {2021-01-01},

journal = {Pneumon},

volume = {34},

number = {3},

pages = {1-11},

abstract = {Introduction In the ongoing coronavirus disease 2019 (COVID-19) pandemic, even though vaccines have been rolled out and the vaccination campaigns in some countries have already been followed by a decline in number and severity of cases, non-pharmaceutical interventions (NPI) are still playing an important role on COVID-19 management (e.g. social distancing) that are imposed by the authorities and require the public’s adherence and behavioral adjustment. This study aims to identify factors that affect the general public’s attitudes towards the importance of NPI in Greece. Methods This prevalence study, enrolled 657 adults from the general Greek population in order to assess their beliefs and identify possible factors that influence their perceptions of NPI. All associations were assessed through multivariate logistic regression. Results Overall, Greeks considered NPI important for health protection. The participants who were less likely to consider NPI important were men compared to women (OR=1.64; 95% CI: 1.15–2.36},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Acute Cardiorespiratory Responses to Different Exercise Modalities in Chronic Heart Failure Patients-A Pilot Study},

author = {E Karatzanos and P Ferentinos and G Mitsiou and S Dimopoulos and A Ntalianis and S Nanas},

doi = {10.3390/jcdd8120164},

issn = {2308-3425},

year  = {2021},

date = {2021-01-01},

journal = {J Cardiovasc Dev Dis},

volume = {8},

number = {12},

abstract = {The purpose of this study was to compare the acute cardiorespiratory responses and time spent above different %VO(2peak) intensities between three "iso-work" protocols: (a) a high intensity interval training protocol (HIIT), (b) a higher intensity continuous protocol (CON(70)) and (c) a lower intensity continuous protocol (CON(50)) in patients with chronic heart failure (CHF). Ten male CHF patients (aged 55.1 ± 16.2 years) performed in separate days a single session of a HIIT protocol consisted of 4 sets × 4 min cycling at 80% VO(2peak) with 3 min of recovery at 50% VO(2peak), a CON(70) protocol corresponding to 70% VO(2peak) and a CON(50) protocol corresponding to 50% VO(2peak). Cardiopulmonary data were collected by an online gas analysis system. The HIIT and CON(70) elicited higher cardiorespiratory responses compared to CON(50) with no differences between them (p > 0.05). In HIIT and CON(70), patients exercised longer at >80% and >90% VO(2peak). The completion rate was 100% for the three protocols. Not any adverse events were observed in either protocol. Both HIIT and CON(70) elicited a stronger physiological stimulus and required shorter time than CON(50). Both HIIT and CON(70) also induced comparable hemodynamic responses and ventilatory demand.},

note = {2308-3425 

Karatzanos, Eleftherios 

Ferentinos, Panagiotis 

Mitsiou, Georgios 

Dimopoulos, Stavros 

Ntalianis, Argyrios 

Nanas, Serafeim 

Journal Article 

J Cardiovasc Dev Dis. 2021 Nov 26;8(12):164. doi: 10.3390/jcdd8120164.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {The acute and long-term effects of a cardiac rehabilitation program on endothelial progenitor cells in chronic heart failure patients: Comparing two different exercise training protocols},

author = {C Kourek and M Alshamari and G Mitsiou and K Psarra and D Delis and V Linardatou and T Pittaras and A Ntalianis and C Papadopoulos and N Panagopoulou and I Vasileiadis and S Nanas and E Karatzanos},

doi = {10.1016/j.ijcha.2020.100702},

issn = {2352-9067 (Print) 

2352-9067},

year  = {2021},

date = {2021-01-01},

journal = {Int J Cardiol Heart Vasc},

volume = {32},

pages = {100702},

abstract = {BACKGROUND: Vascular endothelial dysfunction is an underlying pathophysiological feature of chronic heart failure (CHF). Endothelial progenitor cells (EPCs) are also impaired. The purpose of the study was to assess the effect of a cardiac rehabilitation (CR) program on the increase of EPCs at rest and on the acute response after maximal exercise in patients with CHF and investigate whether there were differences between two exercise training protocols and patients of NYHA II and III classes. METHODS: Forty-four patients with stable CHF enrolled in a 36-session CR program and were randomized in one training protocol; either high-intensity interval training (HIIT) or HIIT combined with muscle strength (COM). All patients underwent maximum cardiopulmonary exercise testing (CPET) before and after the CR program and venous blood was drawn before and after each CPET. Five endothelial cellular populations, expressed as cells/10(6) enucleated cells, were quantified by flow cytometry. RESULTS: An increase in all endothelial cellular populations at rest was observed after the CR program (p < 0.01). The acute response after maximum exercise increased in 4 out of 5 endothelial cellular populations after rehabilitation. Although there was increase in EPCs at rest and the acute response after rehabilitation in each exercise training group and each NYHA class, there were no differences between HIIT and COM groups or NYHA II and NYHA III classes (p > 0.05). CONCLUSIONS: A 36-session CR program increases the acute response after maximum CPET and stimulates the long-term mobilization of EPCs at rest in patients with CHF. These benefits seem to be similar between HIIT and COM exercise training protocols and between patients of different functional classes.},

note = {2352-9067 

Kourek, Christos 

Alshamari, Manal 

Mitsiou, Georgios 

Psarra, Katherina 

Delis, Dimitrios 

Linardatou, Vasiliki 

Pittaras, Theodoros 

Ntalianis, Argyrios 

Papadopoulos, Costas 

Panagopoulou, Niki 

Vasileiadis, Ioannis 

Nanas, Serafim 

Karatzanos, Eleftherios 

Journal Article 

Int J Cardiol Heart Vasc. 2020 Dec 24;32:100702. doi: 10.1016/j.ijcha.2020.100702. eCollection 2021 Feb.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Endothelial progenitor cells mobilization after maximal exercise in patients with chronic heart failure},

author = {C Kourek and E Karatzanos and K Psarra and A Ntalianis and G Mitsiou and D Delis and V Linardatou and T Pittaras and I Vasileiadis and S Dimopoulos and S Nanas},

doi = {10.1016/j.hjc.2020.03.007},

issn = {1109-9666},

year  = {2021},

date = {2021-01-01},

journal = {Hellenic J Cardiol},

volume = {62},

number = {1},

pages = {70-72},

note = {2241-5955 

Kourek, Christos 

Karatzanos, Eleftherios 

Psarra, Katherina 

Ntalianis, Argyrios 

Mitsiou, Georgios 

Delis, Dimitrios 

Linardatou, Vasiliki 

Pittaras, Theodoros 

Vasileiadis, Ioannis 

Dimopoulos, Stavros 

Nanas, Serafim 

Letter 

Netherlands 

Hellenic J Cardiol. 2021 Jan-Feb;62(1):70-72. doi: 10.1016/j.hjc.2020.03.007. Epub 2020 Apr 15.},

keywords = {Chronic Disease  *Endothelial Progenitor Cells  Exercise  Exercise Test  *Heart Failure/therapy  Humans  Oxygen Consumption  LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Direct anterior approach vs Hardinge in obese and nonobese osteoarthritic patients: A randomized controlled trial},

author = {G Macheras and S Stasi and M Sarantis and A Triantafyllou and D Tzefronis and S A Papadakis},

doi = {10.5312/wjo.v12.i11.877},

issn = {2218-5836 (Print) 

2218-5836},

year  = {2021},

date = {2021-01-01},

journal = {World J Orthop},

volume = {12},

number = {11},

pages = {877-890},

abstract = {BACKGROUND: The increased prevalence of obesity has resulted in orthopedic surgeons being likely to face many patients with a high body mass index (BMI) who warrant total hip arthroplasties (THAs) over the coming years. Studies' findings considered the postoperative clinical, and functional outcomes in these patients are controversial, and selecting the most appropriate surgical approach remains debatable. AIM: To compare pain-levels, functionality, and quality-of-life in obese and nonobese osteoarthritic patients who have undergone primary total hip arthroplasty through either direct-anterior-approach (DAA) or Hardinge-approach. METHODS: One hundred and twenty participants (> 50 years) were divided into four groups according to the surgical approach (DAA or Hardinge) and patients' BMI (nonobese < 30 kg/m(2) vs obese ≥ 30 kg/m(2)). Outcomes were measured preoperatively and postoperatively (6(th) and 12(th) week). Pain was measured with Face Pain Scale-Revised (FPS-R). Functionality was measured with Timed Up & Go (TUG) test and Modified Harris Hip Score-Greek version (MHHS-Gr). Quality-of-life was evaluated with the 12-item-International Hip Outcome Tool-Greek version (iHOT12-Gr) (Clinical Trial Identifier: ISRCTN15066737). RESULTS: DAA vs Hardinge: (week 6) DAA-patients showed 12.2% less pain, more functionality (14.8% shorter TUG-performance time, 21.5% higher MHHS-Gr), and 38.16% better quality-of-life (iHOT12-Gr) compared to Hardinge-patients (all P values < 0.001). These differences were further increased on week 12 (all P values ≤ 0.05)]. DAA-obese vs Hardinge-obese: (week 6) DAA-obese patients had less pain, shorter TUG-performance time, better MHHS-Gr and iHOT12-Gr scores than Hardinge-obese (all P values < 0.01). (Week 12) Only the TUG-performance time of DAA-obese was significantly shortened (22.57%, P < 0.001). DAA-nonobese vs DAA-obese: no statistically significant differences were observed comparing the 6(th) and 12(th) weeks' outcomes. CONCLUSION: DAA-groups reported less pain, more functionality and better quality-of-life, compared to the Hardinge-groups. The DAA benefited obese and nonobese patients, similarly yet faster, suggesting that it should be the more preferred choice for obese patients, instead of Hardinge. However, more comparative studies with more extended follow-up periods are needed to confirm our results and better evaluate all patients' long-term outcomes.},

note = {2218-5836 

Macheras, George 

Stasi, Sophia 

Sarantis, Michail 

Triantafyllou, Athanasios 

Tzefronis, Dimitrios 

Papadakis, Stamatios A 

Clinical Trial 

World J Orthop. 2021 Nov 18;12(11):877-890. doi: 10.5312/wjo.v12.i11.877. eCollection 2021 Nov 18.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Lymphedema duration as a predictive factor of efficacy of complete decongestive therapy},

author = {E Michopoulos and G Papathanasiou and K Krousaniotaki and I Vathiotis and T Troupis and E Dimakakos},

issn = {0024-7766},

year  = {2021},

date = {2021-01-01},

journal = {Lymphology},

volume = {54},

number = {3},

pages = {140-153},

abstract = {Lymphedema is a common condition with global impact and a multitude of complications, however, only a few professionals specialize in its management. A retrospective analysis of 105 subjects with unilateral lymphedema upper or lower limb was performed to investigate whether the duration of lymphedema constitutes an important factor associated with the efficacy of complete decongestive therapy (CDT). Subjects were classified into two groups according to the duration of lymphedema, prior to CDT: group A (≤1 year) and group B (>1 year). Both groups were treated daily according to the same CDT protocol for four weeks. The CDT efficacy was determined based on the percent reduction of excess volume (PREV) measurements. Lymphedema was significantly reduced in both groups of subjects, but significantly more in group A (p<0.001). In subjects with upper limb lymphedema, median value of PREV was 80.8% (interquartile range, 79.1-105.0%) in group A and 62.0% (interquartile range, 56.7-66.5%) in group B (p<0.001). In subjects with lower limb lymphedema PREV was 80.7% (interquartile range, 74.9-85.2%) and 64.5% (interquartile range, 56.0-68.1%) for groups A and B, respectively (p<0.001). Duration of lymphedema was found to be a strong predictive factor that may significantly impact CDT efficacy. Therapeutic effects were increased in subjects who were detected and treated earlier for lymphedema.},

note = {2522-7963 

Michopoulos, E 

Papathanasiou, G 

Krousaniotaki, K 

Vathiotis, I 

Troupis, T 

Dimakakos, E 

Journal Article 

United States 

Lymphology. 2021;54(3):140-153.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Multimodal Neurophysiological and Neuroimaging Evidence of Genetic Influence on Motor Control: A Case Report of Monozygotic Twins},

author = {M Papadopoulou and E Karavasilis and F Christidi and G D Argyropoulos and I Skitsa and G Makrydakis and E Efstathopoulos and T Zambelis and N Karandreas},

doi = {10.1097/wnn.0000000000000262},

issn = {1543-3633},

year  = {2021},

date = {2021-01-01},

journal = {Cogn Behav Neurol},

volume = {34},

number = {1},

pages = {53-62},

abstract = {Considering genetic influence on brain structure and function, including motor control, we report a case of right-handed monozygotic twins with atypical organization of fine motor movement control that might imply genetic influence. Structural and functional organization of the twins' motor function was assessed using transcranial magnetic stimulation (TMS), fMRI with a motor-task paradigm, and diffusion tensor imaging (DTI) tractography. TMS revealed that both twins presented the same unexpected activation and inhibition of both motor cortices during volitional unilateral fine hand movement. The right ipsilateral corticospinal tract was weaker than the left contralateral one. The motor-task fMRI identified activation in the left primary motor cortex and bilateral secondary motor areas during right-hand (dominant) movement and activation in the bilateral primary motor cortex and secondary motor areas during left-hand movement. Based on DTI tractography, both twins showed a significantly lower streamline count (number of fibers) in the right corticospinal tract compared with a control group, which was not the case for the left corticospinal tract. Neither twin reported any difficulty in conducting fine motor movements during their activities of daily living. The combination of TMS and advanced neuroimaging techniques identified an atypical motor control organization that might be influenced by genetic factors. This combination emphasizes that activation of the unilateral uncrossed pyramidal tract represents an alternative scheme to a "failure" of building a standard pattern but may not necessarily lead to disability.},

note = {1543-3641 

Papadopoulou, Marianna 

Karavasilis, Efstratios 

Christidi, Foteini 

Argyropoulos, Georgios D 

Skitsa, Ioulia 

Makrydakis, George 

Efstathopoulos, Efstathios 

Zambelis, Thomas 

Karandreas, Nikolaos 

Case Reports 

Journal Article 

United States 

Cogn Behav Neurol. 2021 Mar 3;34(1):53-62. doi: 10.1097/WNN.0000000000000262.},

keywords = {Adult  Functional Laterality/*genetics  Humans  Male  Neuroimaging/*methods  Neurophysiology/*methods  Twins, Monozygotic  LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Neurophysiological and ultrasonographic comparative study of autonomous nervous system in patients suffering from fibromyalgia and generalized anxiety disorder},

author = {M Papadopoulou and A Papapostolou and E Bakola and V G Masdrakis and C Moschovos and E Chroni and G Tsivgoulis and I Michopoulos},

doi = {10.1007/s10072-021-05606-3},

issn = {1590-1874},

year  = {2021},

date = {2021-01-01},

journal = {Neurol Sci},

abstract = {BACKGROUND: Fibromyalgia (FM) and generalized anxiety disorder (GAD) share common clinical features: they both affect women more than men, their diagnosis is based solely on clinical criteria, and some of the symptoms such as anxiety, aches and muscle tension, sleep disorders, and cognitive dysfunction occur in both diseases. For both conditions, an underlying dysregulation of the autonomic nervous system (ANS) has been proposed. OBJECTIVE: The aims of this study were to investigate ANS dysfunction in FM and GAD and compare them with controls. METHODS: Sympathetic skin response (SSR) from palm and sole and cross-sectional area (CSA) of bilateral vagus nerves (VN) were measured in 28 healthy controls, 21 FM patients, and 24 GAD patients. RESULTS: CSA of VN was significantly smaller in FM patients (right: 1.97 ± 0.74mm(2), left: 1.75 ± 0.65 mm2) and GAD patients (right: 2.12 ± 0.97mm(2), left: 1.71 ± 0.86 mm(2)) compared to controls (right: 3.21 ± 0.75 mm(2), left: 2.65 ± 1.13 mm(2), p < 0.001, but did not differ between the two patient groups. SSR parameters were similar between patients and controls. SSR latency correlated to clinical scales (FM Widespread Pain Index) in the FM group (r = 0.515, p = 0.02 and r = 0.447, p = 0.05) for the upper and lower limbs respectively, but no other correlation between clinical and neurophysiological parameters was identified. CONCLUSION: This study confirms similar ANS abnormalities in FM and GAD that fairly distinguish them from controls and support the hypothesis of a common pathophysiological substrate underlying both conditions.},

note = {1590-3478 

Papadopoulou, Marianna 

Papapostolou, Apostolos 

Bakola, Eleni 

Masdrakis, Vasilios G 

Moschovos, Christos 

Chroni, Elisabeth 

Tsivgoulis, Georgios 

Michopoulos, Ioannis 

Journal Article 

Italy 

Neurol Sci. 2021 Sep 24. doi: 10.1007/s10072-021-05606-3.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Association of Psychometric Indices and Normal Electrodiagnostic Studies in Referral for Suspected Carpal Tunnel Syndrome},

author = {M Papadopoulou and G Tsivgoulis and I Chatzi and L Palaiodimou and M Bregianni and K Voumvourakis and I Michopoulos},

doi = {10.21873/invivo.12439},

issn = {0258-851X (Print) 

0258-851x},

year  = {2021},

date = {2021-01-01},

journal = {In Vivo},

volume = {35},

number = {3},

pages = {1791-1797},

abstract = {BACKGROUND/AIM: The aim of this study was to investigate psychometric indices and their association with electrodiagnostic studies (EDX). PATIENTS AND METHODS: A total of 100 patients referred for EDX testing of the upper limbs were prospectively enrolled. Demographic data, laboratory test results, referral physician specialty, main symptom, WHODAS 2.0-12 item version, Hospital Anxiety and Depression Scale (HADS), Boston Carpal Tunnel Questionnaire (BCTQ) and a Numeric Rating Scale (NRS) indicating the extent of their discomfort were collected. RESULTS: Normal EDX results were elicited from 56% of patients. Only the presence of numbness in the right hand, pain in the left hand and older age were significantly associated with an abnormal EDX result. The more depressed and anxious the patients were, the more they scored on psychometric scales. CONCLUSION: The large prevalence of normal EDX studies raises the issue of unnecessary referrals. A proportion of patients are referred only according to their reported symptoms. Psychological factors affect the way a person expresses physical discomfort, leading to unnecessary EDX referrals and inevitably with normal results.},

note = {1791-7549 

Papadopoulou, Marianna 

Tsivgoulis, Georgios 

Chatzi, Ioanna 

Palaiodimou, Lina 

Bregianni, Marianna 

Voumvourakis, Konstantinos 

Michopoulos, Ioannis 

Journal Article 

In Vivo. 2021 May-Jun;35(3):1791-1797. doi: 10.21873/invivo.12439.},

keywords = {Aged  Anxiety/diagnosis/epidemiology  *Carpal Tunnel Syndrome/diagnosis/epidemiology  Hand  Humans  Psychometrics  Referral and Consultation  LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {The effects of cognitive behavioural therapy delivered by physical therapists in knee osteoarthritis pain: A systematic review and meta-analysis of randomized controlled trials},

author = {A Pitsillides and D Stasinopoulos and K Giannakou},

doi = {10.1016/j.jbmt.2020.11.002},

issn = {1360-8592},

year  = {2021},

date = {2021-01-01},

journal = {J Bodyw Mov Ther},

volume = {25},

pages = {157-164},

abstract = {BACKGROUND: Recent evidence suggests that knee osteoarthritis (KOA) chronic pain can result in brain structural and organizational changes. Thus, patients' pain level, emotional status, and perception of their condition might be negatively altered. An approach to reverse such adaptations to chronic pain is cognitive behavioural therapy (CBT). Combining CBT with exercise might enhance therapy outcomes. OBJECTIVES: To identify the effect of combining exercise and CBT when delivered by a physical therapist in KOA pain. METHODS: A systematic search in PubMed, Cochrane, and Medline Complete (EBSCO) databases was conducted from their inception to March 2020, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Study risk of bias and quality were assessed through the Risk-of-bias 2 (ROB2) and PEDro scales. RESULTS: Six primary studies met eligibility criteria. All studies had a low risk of bias and were divided into two sub-groups, in-person interventions and distance interventions. Both groups of studies showed within group participant improvements. In regards of WOMAC pain subscale, our meta-analysis revealed an overall deduction of -1.42 (95% CI: -1.76, -1.09; I(2) = 58%), -1.62 (95% CI: -1.97, -1.27; I(2) = 0%) in centre-based intervention, and -1.28 (95% CI: -1.75, -0.81; I(2) = 73%) in distance delivered intervention. CONCLUSION: Combining exercise and CBT seems to be an effective method to reduce KOA pain, although it is based on a small number of studies. Further studies are needed to reveal any differences when each intervention is applied separately.},

note = {1532-9283 

Pitsillides, Alexios 

Stasinopoulos, Dimitrios 

Giannakou, Konstantinos 

Journal Article 

Meta-Analysis 

Review 

Systematic Review 

United States 

J Bodyw Mov Ther. 2021 Jan;25:157-164. doi: 10.1016/j.jbmt.2020.11.002. Epub 2020 Nov 6.},

keywords = {*Chronic Pain  *Cognitive Behavioral Therapy  Humans  *Osteoarthritis, Knee/therapy  *Physical Therapists  Randomized Controlled Trials as Topic  LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Healing potential of the anterior cruciate ligament in terms of fiber continuity after a complete rupture: A systematic review},

author = {A Pitsillides and D Stasinopoulos and K Giannakou},

doi = {10.1016/j.jbmt.2021.06.003},

issn = {1360-8592},

year  = {2021},

date = {2021-01-01},

journal = {J Bodyw Mov Ther},

volume = {28},

pages = {246-254},

abstract = {INTRODUCTION: Complete rupture of the anterior cruciate ligament is a major problem owing to inadequate surgery outcomes and the limited healing capacity of the ligament. This study aimed to summarise the evidence on the spontaneous healing potential of the anterior cruciate ligament in terms of fiber continuity based on magnetic resonance imaging (MRI) findings. METHODS: PubMed, Cochrane Library, Scopus, and MEDLINE databases were searched from their inception to November 1, 2020. Studies that analysed patients diagnosed with complete anterior cruciate ligament rupture were included. Further, studies that used conservative treatment as intervention and MRI finding as an outcome measure were included. RESULTS: In total, 9 studies, with a total of 734 participants, met the inclusion criteria. Knee laxity was measured in all studies. Two studies classified patients according to rupture location, where most ligaments with restored fiber continuity had proximal ruptures. All included studies reported spontaneous healing. Furthermore, none of the included studies reported the absence of healing. CONCLUSIONS: This systematic review demonstrates the intrinsic healing capacity of the anterior cruciate ligament, indicating a higher healing potential for proximal ruptures. While our study reveals an emerging need to question general practice, a definitive conclusion could not be drawn owing to the low quality of the studies included and the heterogeneity of results.},

note = {1532-9283 

Pitsillides, Alexios 

Stasinopoulos, Dimitrios 

Giannakou, Konstantinos 

Journal Article 

Review 

United States 

J Bodyw Mov Ther. 2021 Oct;28:246-254. doi: 10.1016/j.jbmt.2021.06.003. Epub 2021 Jun 12.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Blood flow restriction training in patients with knee osteoarthritis: Systematic review of randomized controlled trials},

author = {A Pitsillides and D Stasinopoulos and I Mamais},

doi = {10.1016/j.jbmt.2021.04.015},

issn = {1360-8592},

year  = {2021},

date = {2021-01-01},

journal = {J Bodyw Mov Ther},

volume = {27},

pages = {477-486},

abstract = {INTRODUCTION: Knee osteoarthritis (KOA) is one of the most common musculoskeletal disorders in the elderly. The patient experiences reduction in muscle strength, pain, joint stiffness and consequently a reduction in quality of life. Whereas high intensity training (HI-TR) is the most effective in the general elderly population, in KOA patients, painless alternatives might be more suitable, since pain can be a deterrent for exercising. Research interest has increased in blood flow restriction training (BFR-TR) due to the observation that, in this specific population, BFR-TR results in equal muscular adaptions to HI-TR but with less join discomfort/pain. OBJECTIVE: We aimed to: (1) determine the value of BFR-TR in patients with KOA and (2) examine which exercise guidelines applied to healthy elderly populations can be adopted for patients suffering from this knee pathology. METHODOLOGY: We searched the literature from the database inception to 2019 through PubMed, Cochrane, and Medline (EBSCO). The inclusion criteria were determined using PICOS principles. We assessed methodology using the Risk of Bias 2 tool and the Pedro scale. Conclusions were extracted with the use of best evidence synthesis. RESULTS: The literature search yielded 45 articles. After screening, three studies matched the inclusion criteria. The included studies were analyzed and discussed. All the included studies reported within group improvements for BFR-TR regarding pain and strength. CONCLUSION: Although the evidence of BFR-TR efficacy on KOA remains scarce, the results favor its use for muscle strengthening and pain reduction in KOA. Further high-quality studies with larger samples are required.},

note = {1532-9283 

Pitsillides, Alexios 

Stasinopoulos, Dimitrios 

Mamais, Ioannis 

Journal Article 

Review 

United States 

J Bodyw Mov Ther. 2021 Jul;27:477-486. doi: 10.1016/j.jbmt.2021.04.015. Epub 2021 Apr 23.},

keywords = {Aged  Humans  Knee Joint  Muscle Strength  *Osteoarthritis, Knee  Quality of Life  Randomized Controlled Trials as Topic  Regional Blood Flow  *Resistance Training  LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {The effect of lumbar spine manipulation on pain and disability in Achilles tendinopathy. A case report},

author = {C Savva and M Kleitou and M Efstathiou and V Korakakis and D Stasinopoulos and C Karayiannis},

doi = {10.1016/j.jbmt.2020.08.014},

issn = {1360-8592},

year  = {2021},

date = {2021-01-01},

journal = {J Bodyw Mov Ther},

volume = {26},

pages = {214-219},

abstract = {BACKGROUND/PURPOSE: Cervical and thoracic spine manipulation has been found to reduce tendon pain and disability in lateral epicondylalgia and rotator cuff tendinopathy. Based on these findings, the application of lumbar spine manipulation may also provide similar improvements in Achilles tendinopathy (AT). Therefore, the purpose of this study was to evaluate the effect of lumbar spine manipulation on pain and disability in a patient experiencing AT. CASE DESCRIPTION: A 44 years old male ex-football player presented with a 20-year history of persistent Achilles tendon pain (ATP) consistent with AT diagnosis. The patient attended 12 treatment sessions receiving a high-velocity, low amplitude lumbar spine manipulation. Outcome measures were collected at baseline, 2 weeks, 4 weeks, 3 months and 6 months and included pain in visual analogue scale, the American Orthopedic Foot and Ankle Score, the 36-Item Short Form Health Survey and the Victorian Institute of Sport Assessment-Achilles questionnaire. Pressure pain threshold was also assessed using an electronic pressure algometer. OUTCOMES: Improvement in all outcome measures was noted 6-months post intervention. Outcome measures indicated substantial improvements in both the patient's pain and disability. The patient was able to perform activities of daily living without difficulties, suggesting higher level of function and quality of life at 6-months post initial evaluation. CONCLUSION: These findings have demonstrated the positive effects of lumbar spine manipulation on ATP and disability. Further studies, specifically clinical trials investigating the effect of lumbar spine manipulation or combining this technique with exercises and functional activities are suggested.},

note = {1532-9283 

Savva, Christos 

Kleitou, Michalis 

Efstathiou, Michalis 

Korakakis, Vasileios 

Stasinopoulos, Dimitris 

Karayiannis, Christos 

Case Reports 

United States 

J Bodyw Mov Ther. 2021 Apr;26:214-219. doi: 10.1016/j.jbmt.2020.08.014. Epub 2020 Sep 8.},

keywords = {*Achilles Tendon  Activities of Daily Living  Adult  Humans  Lumbar Vertebrae  Male  *Musculoskeletal Pain  Quality of Life  *Tendinopathy/therapy  Treatment Outcome  LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Modified Harris Hip Score as patient-reported outcome measure in osteoarthritic patients: psychometric properties of the Greek version},

author = {S Stasi and G Papathanasiou and A Diochnou and B Polikreti and A Chalimourdas and G A Macheras},

doi = {10.1177/1120700020901682},

issn = {1120-7000},

year  = {2021},

date = {2021-01-01},

journal = {Hip Int},

volume = {31},

number = {4},

pages = {516-525},

abstract = {INTRODUCTION: This study explored the psychometric properties of the modified Harris Hip Score-Greek version (mHHS-Gr) as a patient-reported outcome (PRO) measure in osteoarthritic hip patients. METHODS: Internal consistency, test-retest reliability and reproducibility were evaluated in 90 patients aged >55 years. Construct validity was tested against Greek versions of the Lower Extremity Functional Scale (LEFS-Greek) and WOMAC Index (WOMAC-Gr), and the Timed Up and Go (TUG) and 9-stairs-ascend/descend (9S-A/D) tests. Known-groups validity was examined using TUG score (cut-off 13.5 s) as an estimate variable. Responsiveness was examined before and 4 weeks after direct anterior minimal invasive surgery. RESULTS: Reliability: Internal consistency was moderate (Cronbach's a = 0.614, p < 0.001). Test-retest reliability was excellent (ICC = 0.881, 95% CI, 0.824-0.920). Reproducibility: Floor and ceiling effects were both 1.1%; measurement error was 3.54 (p < 0.05); minimal important change was lower than minimal detectable change.Validity: mHHS-Gr correlated strongly with both LEFS-Greek and WOMAC-Gr (Pearson's r 0.801 and -0.783, respectively; p < 0.001). The questionnaire's correlations with TUG and 9S-A/D were also significant but moderate (Spearman's ρ: -0.547 and -0.575, respectively; p < 0.001). Known-groups validity showed that mHHS-Gr scores were significantly higher in participants with TUG < 13.5 seconds than in those with TUG > 13.5 seconds (p < 0.001). In ROC analysis, the cut-off point of 52.5 yielded sensitivity 81% and specificity 71%.Responsiveness: Standardised response mean and Guyatt's responsiveness statistic were greater than 0.8. DISCUSSION: mHHS-Gr showed significant moderate to excellent reliability, significant moderate to strong validity properties and excellent responsiveness. Overall, mHHS-Gr could be a reliable and valid PRO measure for assessing patients with osteoarthritis of the hip.},

note = {1724-6067 

Stasi, Sophia 

Papathanasiou, George 

Diochnou, Afroditi 

Polikreti, Basiliki 

Chalimourdas, Antonios 

Macheras, George A 

Journal Article 

United States 

Hip Int. 2021 Jul;31(4):516-525. doi: 10.1177/1120700020901682. Epub 2020 Jan 27.},

keywords = {Humans  *Patient Reported Outcome Measures  Psychometrics  ROC Curve  Reproducibility of Results  Surveys and Questionnaires  LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Letter to the Editor on: "Effects of Exercise Training on the Paracrine Function of Circulating Angiogenic Cells."},

author = {S P Tokmakidis and G Mitsiou and I Smilios and S Nanas},

doi = {10.1055/a-1527-5012},

issn = {0172-4622},

year  = {2021},

date = {2021-01-01},

journal = {Int J Sports Med},

volume = {42},

number = {12},

pages = {1137-1138},

note = {1439-3964 

Tokmakidis, S P 

Mitsiou, G 

Smilios, I 

Nanas, S 

Comment 

Letter 

Germany 

Int J Sports Med. 2021 Nov;42(12):1137-1138. doi: 10.1055/a-1527-5012. Epub 2021 Nov 3.},

keywords = {*Cardiovascular Physiological Phenomena  *Exercise  LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Biomechanical assessment of wear in ceramic on ceramic and ceramic on XLPE THAs},

author = {A Triantafyllou and G Papagiannis and S Stasi and G Papathanasiou and P Koulouvaris and P J Papagelopoulos and G C Babis},

url = {https://doi.org/10.1142/S0219519421500238},

doi = {10.1142/S0219519421500238},

issn = {0219-5194},

year  = {2021},

date = {2021-01-01},

journal = {Journal of Mechanics in Medicine and Biology},

volume = {21},

number = {02},

pages = {2150023},

abstract = {Total Hip Arthroplasty (THA) is an effective treatment for severe hip arthritis, with patients reporting high rates of satisfactory results postoperatively. There are a variety of choices regarding THA implant designs. Ceramic on Ceramic and Ceramic on Highly Cross-Linked Polyethylene (XLPE) THAs are the materials of choice nowadays. The purpose of this study is to review the effect of kinematics and kinetics on wear (in vivo and in vitro testing) that affect wear in Ceramic on Ceramic and Ceramic on XLPE total hip arthroplasties and identify possible advantages amongst them. The study hypothesis was that THA kinematics and/or kinetics, since they directly affect THA wear, could provide data for possible advantages between the examined implant designs. A systematic review of the literature identified no significant evidence for biomechanical advantages between these two prostheses in terms of wear. Further research is proposed with the use of gait analysis systems combined with surface electromyography to further investigate THA biomechanics at a laboratory set up. Wearable sensors technology could also identify detailed biomechanical parameters in more complex daily activities.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {The Effect of Intensive Close-Kinetic-Chain Exercises on Functionality and Balance Confidence After Total Knee Arthroplasty},

author = {T Tsonga and S Stasi and G Papathanasiou},

doi = {10.7759/cureus.18965},

issn = {2168-8184 (Print) 

2168-8184},

year  = {2021},

date = {2021-01-01},

journal = {Cureus},

volume = {13},

number = {10},

pages = {e18965},

abstract = {Objectives The aim of this study was to evaluate the effects of an additional close-kinetic-chain exercise program (CKC-PT), in conjunction with the standard physiotherapy intervention (TKA-PT), on the general health status, functionality, balance confidence, and postoperative falls of knee osteoarthritic patients who had undergone total knee arthroplasty (TKA). Patients and methods Thirty community-dwellers, aged >65 years, were randomized into equal groups. The Greek versions of the SF-36 version1.0 (SF-36v1.0-Gr), WOMAC(®) (WOMAC(®)-Gr), Activities-specific Balance Confidence scale (ABC-Greek), Timed Up and Go (TUG) test, and Berg Balance Scale were assessed preoperatively and twice postoperatively (7(th) week and 12(th) month). Non-parametric (Mann-Whitney test) and parametric (two-way analysis of variance (ANOVA) model and student t-test) analyses were used to compare the percentage changes in all variables. Results The CKC-PT group reported better (%) functional improvement (WOMAC(®)-Gr Physical- Function subscale) and higher (%) balance confidence (ABS-Greek) at the seventh week and twelfth month as compared to TKA-PT (p<0.05). No other statistically significant differences were observed. Conclusions The implementation of a close-kinetic-chain exercise program, in addition to standard physiotherapy, may significantly increase both the functionality and balance confidence of patients who have undergone TKA. Further studies are needed to verify these findings.},

note = {2168-8184 

Thonga, Theano 

Stasi, Sophia 

Papathanasiou, George 

Journal Article 

Cureus. 2021 Oct 22;13(10):e18965. doi: 10.7759/cureus.18965. eCollection 2021 Oct.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Is Shoulder Pain and Disability Index a Prognostic Factor for Neuropathic Shoulder Pain?},

author = {S D Vrouva and V K Sopidou and K P Chanopoulos and D F Bakalidou and V C Papatsimpas and N Sorras and M C Ziogas and G A Koumantakis},

doi = {10.7759/cureus.19173},

issn = {2168-8184 (Print) 

2168-8184},

year  = {2021},

date = {2021-01-01},

journal = {Cureus},

volume = {13},

number = {10},

pages = {e19173},

abstract = {Introduction So far, investigations in patients with rotator cuff diseases have used pain measurement tools such as visual analog scale (VAS) for nociceptive pain as well as neuropathic pain (NeuP) specialized ones like Douleur Neuropathique 4 Question (DN4) and Pain Detect. The study's goal was to look at the existence of NeuP in patients with chronic shoulder pain, as well as variables that may be predictive of its progression. Methods There were 112 outpatients in all. Current and previous pain intensity levels were documented with the numerical rating scale (NRS), the Shoulder Pain and Disability Index (SPADI) was used to assess pain and disability levels, and the S-LANSS (self-completed Leeds Assessment of Neuropathic Symptoms and Signs Pain Scale) was used to diagnose NeuP. The Pearson Chi-Square test was employed to check for any relationships between variables. The Mann-Whitney U test was also employed to check for between-group differences (with or without NeuP). To investigate factors that may be utilized as a prognostic for NeuP, logistic regression was performed, with those components (from the univariate analysis) that were statistically significant being included. Results According to the S-LANSS questionnaire for NeuP diagnosis, 21 patients had NeuP. According to S-LANSS, chi-square test findings revealed that NeuP is independent of sex, smoking, size, and location or rotator cuff tear. Univariate analysis with Mann-Whitney U test revealed statistically significant differences in SPADI and NRS scores between the two patient groups (p < 0.001). Α multivariate analysis using S-LANSS as the binary dependent variable and NRS currently, NRS average last month and SPADI total score as independent variables (with statistical significance) revealed that total SPADI score may be considered as an independent prognostic factor for NeuP (odds ratio = 1.189, p < 0.001). Limitations Due to the limited number of patients who participated in the study, the findings were deemed insufficient in terms of statistical power. In particular, the power analysis of the study (type I error probability being [a] = .05) was less than 80% (for the total SPADI score), hence relatively small. As a result, there is a limited probability of a type I error. Conclusions Using S-LANSS, we discovered that 18.8% of patients with rotator cuff tears had NeuP. The SPADI scores (pain and disability) in the NeuP group were substantially greater than in the nociceptive pain group. As previous studies have suggested utilizing certain levels of the VAS for pain assessment and specialized questionnaires for NeuP evaluation, we recommend that SPADI be included as a tool for emphasizing the neuropathic features of shoulder pain.},

note = {2168-8184 

Vrouva, Sotiria D 

Sopidou, Varvara K 

Chanopoulos, Konstantinos P 

Bakalidou, Daphne F 

Papatsimpas, Vasileios C 

Sorras, Nikolaos 

Ziogas, Miltiades C 

Koumantakis, George A 

Journal Article 

Cureus. 2021 Oct 31;13(10):e19173. doi: 10.7759/cureus.19173. eCollection 2021 Oct.},

keywords = {LANECASM  LAdPhyss 2},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {The Effect of Body Position and the Reliability of Upper Limb Arterial Occlusion Pressure Using a Handheld Doppler Ultrasound for Blood Flow Restriction Training},

author = {S. Karanasios and C. Koutri and M. Moutzouri and S. A. Xergia and V. Sakellari and G. Gioftsos},

doi = {10.1177/19417381211043877},

issn = {1941-0921},

year  = {2021},

date = {2021-01-01},

journal = {Sports Health},

pages = {19417381211043877},

abstract = {BACKGROUND: The precise calculation of arterial occlusive pressure is essential to accurately prescribe individualized pressures during blood flow restriction training. Arterial occlusion pressure in the lower limb varies significantly between different body positions while similar reports for the upper limb are lacking. HYPOTHESIS: Body position has a significant effect in upper limb arterial occlusive pressure. Using cuffs with manual pump and a handheld Doppler ultrasound can be a reliable method to determine upper limb arterial blood flow restriction. STUDY DESIGN: A randomized repeated measures design. LEVEL OF EVIDENCE: Level 3. METHODS: Forty-two healthy participants (age mean ± SD = 28.1 ± 7.7 years) completed measurements in supine, seated, and standing position by 3 blinded raters. A cuff with a manual pump and a handheld acoustic ultrasound were used. The Wilcoxon signed-rank test with Bonferroni correction was used to analyze differences between body positions. A within-subject coefficient of variation and an intraclass correlation coefficient (ICC) test were used to calculate reproducibility and reliability, respectively. RESULTS: A significantly higher upper limb arterial occlusive pressure was found in seated compared with supine position (P < 0.031) and in supine compared with standing position (P < 0.031) in all raters. An ICC of 0.894 (95% CI = 0.824-0.939, P < 0.001) was found in supine, 0.973 (95% CI = 0.955-0.985, P < 0.001) in seated, and 0.984 (95% CI = 0.973-0.991, P < 0.001) in standing position. ICC for test-retest reliability was found 0.90 (95% CI = 0.814-0.946, P < 0.001), 0.873 (95% CI = 0.762-0.93, P < 0.001), and 0.858 (95% CI = 0.737-0.923, P < 0.001) in the supine, seated, and standing position, respectively. CONCLUSION: Upper limb arterial occlusive pressure was significantly dependent on body position. The method showed excellent interrater reliability and repeatability between different days. CLINICAL RELEVANCE: Prescription of individualized pressures during blood flow restriction training requires measurement of upper limb arterial occlusive pressure in the appropriate position. The use of occlusion cuffs with a manual pump and a handheld Doppler ultrasound showed excellent reliability; however, the increased measurement error compared with the differences in arterial occlusive pressure between certain positions should be carefully considered for the clinical application of the method. STRENGTH OF RECOMMENDATIONS TAXONOMY (SORT): B.},

note = {1941-0921 

 

Journal Article 

United States 

Sports Health. 2021 Sep 13:19417381211043877. doi: 10.1177/19417381211043877.},

keywords = {Kaatsu training; arterial occlusion; blood flow restriction training; reliability},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Active Joint Position Sense in Children With Unilateral Cerebral Palsy},

author = {N. Chrysagis and G. A. Koumantakis and E. Grammatopoulou and E. Skordilis},

doi = {10.7759/cureus.18075},

issn = {2168-8184 (Print) 

2168-8184},

year  = {2021},

date = {2021-01-01},

journal = {Cureus},

volume = {13},

number = {9},

pages = {e18075},

abstract = {Objective The aim of the study was to examine the differences in joint position sense at the elbow joint between 15 children with unilateral cerebral palsy (CP) and 15 typically developing (TD) controls without neurological or other health deficits. Methodology Joint position sense, a major proprioceptive component, was evaluated actively using a Kin Com 125 AP isokinetic dynamometer (Chattanooga Group, Chattanooga, TN). Results A significant interaction was found (p<0.05) between disability and side, with respect to the active reproduction movement scores. Post-hoc independent t-tests, with Bonferroni adjustments, revealed significant differences for the dominant (t=-3.63},

note = {2168-8184 

Chrysagis, Nikolaos 

Koumantakis, George A 

Grammatopoulou, Eirini 

Skordilis, Emmanouil 

Journal Article 

Cureus. 2021 Sep 18;13(9):e18075. doi: 10.7759/cureus.18075. eCollection 2021 Sep.},

keywords = {assessment; cerebral palsy; hemiplegia; position sense; proprioception; spasticity},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Effectiveness of Treadmill Training on Walking Ability in Adults with Cerebral Palsy: A Systematic Review and Meta-Analysis},

author = {N. Chrysagis and G. Theotokatos and E. Skordilis and V. Sakellari and E. Grammatopoulou and G. A. Koumantakis},

url = {http://www.journals.aiac.org.au/index.php/IJKSS/article/view/6998},

doi = {10.7575/aiac.ijkss.v.9n.4p.34},

issn = {2202-946X},

year  = {2021},

date = {2021-01-01},

journal = {2021},

volume = {9},

number = {4},

pages = {9},

abstract = {Background: Patients with cerebral palsy (CP) may necessitate long-term treatment and monitoring of their condition, not only during the period of development but also during adulthood. Objectives: This systematic review aimed to analyze evidence from randomized controlled trials (RCTs) that have investigated the effect of treadmill training on walking ability in adults with cerebral palsy. Methods: RCTs were identified and selected systematically, with appropriate keywords applied in four scientific databases (Medline, Scopus, the Cochrane Library, and the Physiotherapy Evidence Database) and one bibliographic search engine (Google Scholar) from January 1980 to September 2021. Two assessors extracted and analyzed data from relevant RCTs published in English and then independently rated those studies for risk of bias with the Risk of Bias (RoB 2) tool. Results: Out of the 96 studies that were initially identified, 93 were excluded, as these either did not meet the inclusion criteria or were duplicates. Three clinical trials were finally included, characterized by some concerns and a high risk of bias (RoB 2). Meta-analysis was only performed for the maximum distance in the ‘6-minute walk for distance test’, due to differences in the remaining outcomes utilized between studies. Overall, there was evidence of some concerns and high risk of bias that treadmill training did not significantly improve the walking ability in adult patients with CP relative to the control conditions. Conclusion: More high-quality RCTs are required, examining the effectiveness of treadmill training on different aspects of walking ability such as gait speed, endurance, and energy expenditure.},

keywords = {cerebral palsy; adults; treadmill; exercise; physical therapy; walking; gait},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {The Effect of the Special Olympics’ Unified Program upon the Attitudes towards Inclusion of Students with Intellectual Disabilities in Greece.},

author = {F. Karkaletsi and G. Theotokatos and N. Chrysagis and Z. Tsifopanopoulou and T. Staebler and V. Papadopoulou and M. Yin and M. Hussey and A. Vougiouka and E. Skordilis},

doi = {10.4236/ape.2021.114038},

year  = {2021},

date = {2021-01-01},

journal = {Advances in Physical Education},

volume = {11},

pages = {460-480},

keywords = {inclusion, Special Olympics, unified sports; attitudes; intellectual disability},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Paraspinal strength and electromyographic fatigue in patients with sub-acute back pain and controls: Reliability, clinical applicability and between-group differences},

author = {G. A. Koumantakis and J. A. Oldham},

doi = {10.5312/wjo.v12.i11.816},

issn = {2218-5836 (Print) 

2218-5836},

year  = {2021},

date = {2021-01-01},

journal = {World J Orthop},

volume = {12},

number = {11},

pages = {816-832},

abstract = {BACKGROUND: Paraspinal muscle strength and fatigue are considered important in low back pain (LBP) prevention and rehabilitation. High reliability of paraspinal strength and electromyographic (EMG)-fatigue parameters has not been universally reported. Moreover, the discriminative validity of these parameters requires further exploration, under the threat of potentially poor reliability of the methods examined. AIM: To investigate the reliability and discriminative validity of paraspinal strength and EMG-related fatigue in subjects with recurrent LBP and healthy participants. METHODS: Test-retest measurements were performed in 26 healthy and 66 LBP volunteers, for reliability. Paraspinal isometric maximal and mean strength were determined with a maximum voluntary isometric contraction (MVIC) protocol, performed in a custom-made device. For the fatigue test, participants performed a 60% MIVC level continuous isometric contraction of the paraspinals, in conjunction with EMG analysis from 4 muscle sites of the lumbar spine. Initial median frequency (IMF), the median frequency slope (MFslope), as well as the root mean square (RMS) slope EMG parameters were used as fatigue measures. Data were analysed with repeated measures ANOVA for test-retest differences. For reliability, the intraclass correlation coefficient (ICC(3,1)), standard error of the measurement (SEM) and the smallest detectable difference (SDD) were reported. Group-related differences for fatigue measures were analysed with a Multivariate Analysis of Covariance, with age, weight and strength as covariates. RESULTS: Isometric strength presented statistically significant between-day differences (P < 0.01), however these did not exceed 10% (healthy: 7.2%/LBP-patients: 9.7%) and ICC reliability values were excellent, yet test-retest error was increased for the patient group (healthy: ICC(3,1): 0.92-0.96, SEM: 5.72-5.94 Hz, SDD: 18.51%-18.57%/LBP-patients: ICC(3,1): 0.91-0.96, SEM: 6.49-6.96, SDD: 30.75%-31.61%). For the frequency data, IMF reliability was excellent (healthy: ICC(3,1): 0.91-0.94, SEM: 3.45-7.27 Hz, SDD: 9.56%-20.14%/patients: ICC(3,1): 0.90-0.94, SEM: 6.41-7.59 Hz, SDD: 17.75%-21.02%) and of MF raw and normalised slopes was good (healthy: ICC(3,1): 0.78-0.82, SEM: 4.93-6.02 Hz, SDD: 13.66-16.67%/LBP-patients: ICC(3,1): 0.83-0.85, SEM: 6.75-7.47 Hz, SDD: 18.69%-20.69%). However, the reliability for RMS data presented unacceptably high SDD values and were not considered further. For discriminative validity, less MVIC and less steep MFslopes were registered for the patient group (P < 0.01). CONCLUSION: Reliability and discriminative ability of paraspinal strength and EMG-related frequency parameters were demonstrated in healthy participants and patients with LBP.},

note = {2218-5836 

Koumantakis, George A 

Oldham, Jacqueline A 

Journal Article 

World J Orthop. 2021 Nov 18;12(11):816-832. doi: 10.5312/wjo.v12.i11.816. eCollection 2021 Nov 18.},

keywords = {low back pain; multifidus; power spectral analysis; reliability; surface electromyography},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Chronic Whiplash Syndrome: Associated Disorders and Physiotherapy Management – A Literature Review},

author = {G. A. Koumantakis and A. Tsiampokalou and N. Chrysagis and E. Grammatopoulou and P. Tatsios},

url = {https://journals.scholarpublishing.org/index.php/JBEMi/article/view/11137},

doi = {10.14738/jbemi.85.11137},

year  = {2021},

date = {2021-01-01},

journal = {British Journal of Healthcare and Medical Research},

volume = {8},

number = {5},

pages = {12-37},

abstract = {<p>\emph{Purpose: }The purpose of the current literature review is to present the Whiplash Associated-Disorders through diagnosis, scales, physical examination and to identify the most suitable physiotherapy management of these conditions. The long-term effectiveness of physiotherapy interventions is also examined.</p><p>\emph{Methods:} Sixteen randomized controlled trials (RCTs) and seven case-control and cohort studies related to chronic WAD fulfilled the inclusion and exclusion criteria. The design, diagnosis, population, methodology, results, methodological quality and physiotherapy management were examined. The PEDro Scale and the Newcastle-Ottawa Scale were used for the examination of the methodological quality.</p><p>\emph{Results:} The methodological quality of the studies used, were high. Significantly important on minimizing the symptoms of chronic WAD were the combination of Exercise therapy &amp; Advice both at 6 and 12 months follow up. Other interventions such as Exercise therapy, Interdisciplinary approach and Multimodal physiotherapy treatment, Spinal Manual therapy and Advice were not equally effective in the long-term.</p><p>\emph{Conclusion: }The most suitable intervention for the physiotherapy management of chronic WAD, with long-term effectiveness was the combination of Exercise &amp; Advice, which was established with various outcome measures, such as NDI, VAS, NRI and SF-36. On the contrary, Exercise therapy, Interdisciplinary approach and Multimodal physiotherapy treatment, Spinal Manual therapy and Advice were not that effective on minimizing the symptoms of chronic WAD in the long-term.</p>},

keywords = {physiotherapy; neck pain},

pubstate = {published},

tppubtype = {article}

}

@article{Chandrinou2020,

title = {Avascular necrosis of the femoral head: Evaluation of hyperbaric oxygen therapy and quality of life},

author = {A Chandrinou and A Korompeli and E Grammatopoulou and K Gaitanou and K Tsoumakas and G Fildissis},

year  = {2020},

date = {2020-09-01},

journal = {Undersea Hyperb Med},

volume = {47},

number = {4},

pages = {561-569},

keywords = {physiotherapy},

pubstate = {published},

tppubtype = {article}

}

@article{Christakou2020,

title = {Re-injury worry, confidence and attention as predictors of a sport re-injury during a competitive season},

author = {A Christakou and N A Stavrou and M Psychountaki and Y Zervas},

doi = {doi: 10.1080/15438627.2020.1853542},

year  = {2020},

date = {2020-09-01},

journal = {Res Sports Med},

pages = {1-11},

abstract = {Rehabilitation from sport injury involves not only physical, but also psychological considerations. Re-injury worry, confidence and attention are characteristics that may affect athletes’ returning to competition after a sport injury. The study aimed to describe the predictive ability of the re-injury worry, confidence, and attention to the total of re-injuries at the new competitive season. The sample was 80 male athletes with at least three years of competitive experience who had a sport musculoskeletal injury in the last 8 months and had followed properly their physiotherapy program. They were ready for re-entry into competitive sport. They completed on returning to competition: (a) the Causes of the Re-Injury Worry Questionnaire, (b) the Sport Confidence Questionnaire of Rehabilitated Athletes Returning to Competition and (c) the Attention Questionnaire of Rehabilitated Athletes Returning to Competition. The three valid and reliable instruments predict the total of re-injuries at the beginning and at the middle of the competitive season. Future research should be conducted to examine the relationship between the physical and psychological characteristics in re-injury’s prediction from different contact sports.},

keywords = {attention, confidence, re-injury, sport, worry},

pubstate = {published},

tppubtype = {article}

}

@article{Gkikopoulos2020,

title = {Examining re-injury worry, confidence and attention after a sport musculoskeletal injury},

author = {G Gkikopoulos and C Chronopoulou and A Christakou},

doi = {doi: 10.23736/s0022-4707.19.10124-7},

year  = {2020},

date = {2020-09-01},

journal = {J Sports Med Phys Fitness},

volume = {60},

number = {3},

pages = {428-434},

abstract = {Background: 

Sport injury is an unfortunate event which can have a major impact on the injured athletes' psychology. Athletes may experience re-injury worry and low levels of attention and confidence getting back to competition following a sport injury. The aim of the study was to examine re-injury worry, confidence and attention of previously injured athletes, before they returned to competition. 

 

Methods: 

Cross-sectional research design. A total of 52 athletes volunteered for this study, aged 23.1±4.8 years old with a previous musculoskeletal injury during the last year. Participants completed the Causes of Re-Injury Worry Questionnaire, the Sport Confidence Questionnaire of Rehabilitated Athletes Returning to Competition and the Attention Questionnaire of Rehabilitated Athletes Returning to Competition, on their first competitive game after rehabilitation program. 

 

Results: 

The athletes experienced average levels of re-injury worry and distraction attention and high levels of confidence and functional attention. The duration of injury, the medical and physiotherapy treatment and the absence from sport were significantly correlated with the questionnaire factors "Re-injury worry due to opponent's ability", "Functional attention" and "Distraction attention". 

 

Conclusions: 

Psychological characteristics of previously injured athletes may be influenced from the duration of: 1) medical treatment; 2) injury; 3) physiotherapy treatment; and 4) absence from sport, when they return to competition. More research needs to be conducted to confirm the present results.},

keywords = {attention, confide, medical, re-injury, sportnce},

pubstate = {published},

tppubtype = {article}

}

@article{Hayden2020,

title = {Exercise treatment effect modifiers in persistent low back pain: an individual participant data meta-analysis of 3514 participants from 27 randomised controlled trials},

author = {J A Hayden and M N Wilson and S Stewart and J L Cartwright and A O Smith and R D Riley and M van Tulder and T Bendix and F Cecchi and L O P Costa and N Dufour and M L Ferreira and N E Foster and M R Gudavalli and J Hartvigsen and P Helmhout and J Kool and G A Koumantakis and F M Kovacs and T Kuukkanen and A Long and L G Macedo and L A C Machado and C G Maher and W Mehling and G Morone and T Peterson and E Rasmussen-Barr and C G Ryan and T Sjögren and R Smeets and J B Staal and M Unsgaard-Tøndel and H Wajswelner and E W Yeung and C L B P I M -A Group},

doi = {doi: 10.1136/bjsports-2019-101205},

year  = {2020},

date = {2020-09-01},

journal = {Br J Sports Med},

volume = {54},

number = {21},

pages = {1277-1278},

abstract = {Background: 

Low back pain is one of the leading causes of disability worldwide. Exercise therapy is widely recommended to treat persistent non-specific low back pain. While evidence suggests exercise is, on average, moderately effective, there remains uncertainty about which individuals might benefit the most from exercise. 

 

Methods: 

In parallel with a Cochrane review update, we requested individual participant data (IPD) from high-quality randomised clinical trials of adults with our two primary outcomes of interest, pain and functional limitations, and calculated global recovery. We compiled a master data set including baseline participant characteristics, exercise and comparison characteristics, and outcomes at short-term, moderate-term and long-term follow-up. We conducted descriptive analyses and one-stage IPD meta-analysis using multilevel mixed-effects regression of the overall treatment effect and prespecified potential treatment effect modifiers. 

 

Results: 

We received IPD for 27 trials (3514 participants). For studies included in this analysis, compared with no treatment/usual care, exercise therapy on average reduced pain (mean effect/100 (95% CI) −10.7 (−14.1 to –7.4)), a result compatible with a clinically important 20% smallest worthwhile effect. Exercise therapy reduced functional limitations with a clinically important 23% improvement (mean effect/100 (95% CI) −10.2 (−13.2 to –7.3)) at short-term follow-up. Not having heavy physical demands at work and medication use for low back pain were potential treatment effect modifiers—these were associated with superior exercise outcomes relative to non-exercise comparisons. Lower body mass index was also associated with better outcomes in exercise compared with no treatment/usual care. This study was limited by inconsistent availability and measurement of participant characteristics. 

 

Conclusions: 

This study provides potentially useful information to help treat patients and design future studies of exercise interventions that are better matched to specific subgroups.},

keywords = {chronic, exercise, low back pain, participants, physiotherapy},

pubstate = {published},

tppubtype = {article}

}

@article{Mitsiou2020,

title = {Exercise promotes endothelial progenitor cell mobilization in patients with chronic heart failure},

author = {G Mitsiou and E Karatzanos and I Smilios and K Psarra and I Patsaki and H T Douda and A Ntalianis and S Nanas and S P Tokmakidis},

doi = {doi: 10.1093/eurjpc/zwaa046},

year  = {2020},

date = {2020-09-01},

journal = {Eur J Prev Cardiol},

abstract = {Regular exercise affects the vascular system, endothelial function, and facilitates microcirculation in patients with chronic heart failure (CHF). It promotes mobilization of endothelial progenitor cells (EPCs) into circulation which repair dysfunctional or injured endothelium and contribute to angiogenesis. Furthermore, haematopoietic progenitor cells (HPCs), a related cell population with progenitor-like properties, support regeneration and facilitate reparatory mechanisms in the vascular system. During exercise, using either a continuous or an interval training method, EPCs circulate into the bloodstream, ‘home to’ sites of ischaemic vascular injury and promote vascular regeneration.},

note = {Online ahead of print},

keywords = {chronic heart failure, endothelial progenitor cells, exercise},

pubstate = {published},

tppubtype = {article}

}

@article{Moutzouri2020,

title = {“Greek KOOS-Child: a valid, disease specific, diagnostically accurate and responsive PROM in children with knee-related pathology”},

author = {M Moutzouri and P Tsoumpos and T Bania and E Billis and J Gliatis},

doi = {doi: 10.1007/s00167-020-06237-5},

year  = {2020},

date = {2020-09-01},

journal = {Knee Surg Sports Traumatol Arthrosc},

volume = {29},

number = {6},

pages = {1841-1849},

abstract = {Purpose: 

The Knee Injury Osteoarthritis Outcome Score (KOOS)-Child questionnaire is one of the frequently child-friendly measures used in pediatric studies. The aim of this study was to transculturally adapt the Greek version of KOOS-Child and evaluate its clinimetric properties in children with knee disorders. 

 

Methods: 

Children visiting the Outpatients Orthopaedic Clinic of a Greek Paediatric General Hospital were considered eligible if they were aged 8–14 years, had a knee soft tissue injury and associated physical limitations. The transcultural adaptation was based on a multistage backward translation approach. Participants completed the KOOS-Child at their first visit to the orthopedic specialist (baseline), 2 weeks and 3 months after baseline. Content validity of the KOOS-Child was evaluated using general QoL measures (KIDSCREEN and Kid-KINDL) and construct validity was explored by correlating relevant items. Responsiveness was evaluated according to the children’s response on the given orthopeadic treatment. 

 

Results: 

Sample consisted of 59 children (30 males), aged: 11 ± 1.8 years. The KOOS-Child showed high internal consistency (Cronbach’s a: 0.80–0.96). Adequate convergent validity with > 75% relevant a priori hypotheses was confirmed. Construct validity was moderate to strong (Pearson’s r correlations between related KOOS and Kid-KINDL subdimensions: 0.54–0.62). KOOS and KIDSCREEN subdimensions correlations were fair (Pearson’s r correlations: 0.32–0.65). KOOS-Child’s diagnostic accuracy was high. Factor analysis extracted height factors accounting for 76.15% of the total variance, confirmed by the scree plot. Responsiveness was moderate to high with Cohen’s d from 0.6 to 1.4. 

 

Conclusion: 

The Greek version of the KOOS-Child demonstrated excellent internal consistency, good construct validity, diagnostic accuracy and interpretability as well as good responsiveness. The measure could be used across Greek children with orthopaedic knee problems. Generalisability of findings is limited due to the relatively limited cohort.},

keywords = {arthroscopy, knee surgery, sports traumatology},

pubstate = {published},

tppubtype = {article}

}

@article{Paraskevopoulos2020,

title = {Systematic infection control in Greek physiotherapy practices during the COVID-19 pandemic},

author = {E Paraskevopoulos and M Papandreou},

doi = {doi: 10.3233/wor-203186},

year  = {2020},

date = {2020-09-01},

journal = {Work},

volume = {66},

number = {2},

pages = {367-370},

keywords = {covid, pandemic, physiotherapy},

pubstate = {published},

tppubtype = {article}

}

@article{Paraskevopoulos2020b,

title = {Reliability of assessment methods for scapular dyskinesis in asymptomatic subjects: A systematic review},

author = {E Paraskevopoulos and M Papandreou and J Gliatis},

doi = {doi: 10.5152/j.aott.2020.19088},

year  = {2020},

date = {2020-09-01},

journal = {Acta Orthop Traumatol Turc},

volume = {54},

number = {5},

pages = {546-556},

abstract = {Objective: 

The aim of this systematic review was to evaluate the available published evidence on the intra- and inter-rater reliabilities of assessment methods used for identifying and measuring scapular dyskinesis (SD) in asymptomatic subjects. 

 

Methods: 

A systematic electronic literature search was performed in PubMed, Physiotherapy Evidence Database, Scopus, and the Cochrane Library, and studies on the intra- and inter-rater reliabilities of physical examination tests used for identifying SD in asymptomatic people were identified. Methodological quality of the studies meeting the inclusion criteria was assessed using the Quality Appraisal of Reliability Studies (QAREL) checklist by two reviewers. The overall level of evidence of this systematic review was determined by the Modified Cochrane Back Pain Criteria based on previous research which was modified for reliability studies of the shoulder complex. 

 

Results: 

The literature search generated 388 results, and only 14 articles met the inclusion criteria. In these studies, reliabilities of two qualitative and five quantitative methods for the assessment of SD were analyzed. The QAREL checklist revealed that 12 studies had moderate risk of bias and 2 had high risk of bias. Additionally, none of the studies were of high quality. On the basis of the Modified Cochrane Back Pain Criteria, the overall level of evidence was moderate. Most of the studies including quantitative measurement methods found good to excellent inter- and intra-rater reliability values. Most of the studies including qualitative methods found low-to-moderate intra- and inter-rater reliability values. 

 

Conclusion: 

Considering the available published evidence, there is lack of high-quality studies evaluating the inter- and intra-rater reliabilities of qualitative or quantitative methods used for the assessment of SD. There are no qualitative methods with high reliability that are fit for clinical applications. Some quantitative methods with higher reliability are present, but clinicians should be aware of the methodological flaws that studies evaluating these methods suffer from.},

keywords = {evidence, physiotherapy, scapular dyskinesis},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Cross-cultural Adaptation and Psychometric Properties of the Greek Version of the Central Sensitization Inventory},

author = {P Bilika and R Neblett and G Georgoudis and Z Dimitriadis and E Fandridis and N Strimpakos and E Kapreli},

doi = {10.1111/papr.12843},

issn = {1530-7085},

year  = {2020},

date = {2020-01-01},

journal = {Pain Pract},

volume = {20},

number = {2},

pages = {188-196},

abstract = {OBJECTIVES: Recent studies support the opinion that central sensitization (CS) plays an important role in the pathophysiology of many chronic pain conditions. CS refers to hyperexcitability of the central nervous system, which can result in pain hypersensitivity and other somatosensory symptoms. Recognition of CS-related symptomology is crucial in chronic pain evaluation and rehabilitation. The Central Sensitization Inventory (CSI) was created to evaluate symptoms that have been found to be associated with CS. The aim of the current study was the cross-cultural adaptation of the CSI into Greek (CSI-Gr). METHODS: To evaluate discriminate validity, 200 patients with chronic pain and 50 healthy control subjects participated. The sample was divided into 4 diagnostic groups (fibromyalgia, single pain complaints, multiple pain complaints, and a control group) and into 5 CSI severity subgroups, from subclinical to extreme. Convergent validity was determined by evaluation of the relationship between the CSI-Gr and the Pain Catastrophizing Scale (PCS). Additionally, 30 patients completed the CSI a second time for the purpose of a test/retest analysis. RESULTS: The results showed high internal consistency (Cronbach's alpha = 0.994) and test-retest reliability (intraclass correlation coefficient = 0.993). The standard error of measurement was 2.1. The CSI-Gr correlated moderately with the PCS (r = 0.68). Statistically significant differences were found among the 3 comparison groups, with patients who had fibromyalgia reporting the highest CSI severity and healthy control subjects reporting the lowest severity. CONCLUSIONS: As determined in the present study, the CSI-Gr was found to be a reliable and valid tool for recognition of CS-related symptomology.},

note = {1533-2500 

Bilika, Paraskevi 

Neblett, Randy 

Georgoudis, George 

Dimitriadis, Zacharias 

Fandridis, Emmanouil 

Strimpakos, Nikolaos 

Kapreli, Eleni},

keywords = {Central Sensitization Inventory, Chronic pain, cross-cultural adaptation, PHYSIOLAB},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {The impact of fascia iliaca compartment block on chronic postsurgical pain in patients undergoing hip fracture repair},

author = {M Diakomi and M Papaioannou and G Georgoudis and E Argyra and A Mela and I Siafaka and A Makris},

doi = {10.1016/j.jclinane.2020.109801},

issn = {0952-8180},

year  = {2020},

date = {2020-01-01},

journal = {J Clin Anesth},

volume = {64},

pages = {109801},

abstract = {STUDY OBJECTIVE: Chronic postsurgical pain (CPSP), i.e. pain persisting >3 months, may appear after any type of surgery. There is a paucity of literature addressing CPSP development after hip fracture repair and the impact of any analgesic intervention on the development of CPSP in patients after hip fracture surgery. This study is the first aiming to examine the impact of ultrasound-guided fascia iliaca compartment block (USG FICB) on the development of CPSP after hip fracture repair. DESIGN: Prospective randomized study. SETTING: Operating room. PATIENTS: 182 patients scheduled for hip fracture surgery. INTERVENTIONS: Patients were randomized to receive a USG FICB (FICB group) or a sham saline injection (sham FICB group), twenty minutes before positioning for spinal anesthesia. MEASUREMENTS: The hip - related characteristic pain intensity (CPI) at 3- months post-surgery was the primary outcome measure. Presence and severity of hip-related pain at 3- and 6-months post-surgery, numeric rating pain scale (NRS) scores at 6, 24, 36, 48 postoperative hours, total 24-hour tramadol PCA administration and timing of the first tramadol dose, were documented as well. MAIN RESULTS: FICB group presented with lower CPI scores 3- months postoperatively (p < 0.01), as well as lower percentage of patients with high-grade CPSP, 3 and 6 months postoperatively (p < 0.001). FICB group also showed significantly lower NRS scores in all instances, lower total 24 - hour tramadol consumption and higher mean time to first tramadol dose (p < 0.05). The overall sample of 182 patients reported a considerably high incidence of hip -related CPSP (60% at 3 months, 45% at 6 months). CONCLUSIONS: USG FICB in the perioperative setting may reduce the incidence, intensity and severity of CPSP at 3 and 6 months after hip fracture surgery, providing safe and effective postoperative analgesia.},

note = {1873-4529 

Diakomi, Maria 

Papaioannou, Marianna 

Georgoudis, George 

Argyra, Erifili 

Mela, Argyro 

Siafaka, Ioanna 

Makris, Alexandros 

Journal Article 

United States 

J Clin Anesth. 2020 Apr 22;64:109801. doi: 10.1016/j.jclinane.2020.109801.},

keywords = {Acute pain, Chronic pain, Lower extremity, PHYSIOLAB},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Assessing frailty in heart failure},

author = {D Farmakis and M Thodi and M Elpidoforou and G Filippatos},

doi = {10.1002/ejhf.1905},

issn = {1388-9842},

year  = {2020},

date = {2020-01-01},

journal = {Eur J Heart Fail},

volume = {22},

number = {11},

pages = {2134-2137},

note = {1879-0844 

Farmakis, Dimitrios 

Thodi, Maria 

Elpidoforou, Michail 

Filippatos, Gerasimos 

Comment 

Editorial 

England 

Eur J Heart Fail. 2020 Nov;22(11):2134-2137. doi: 10.1002/ejhf.1905. Epub 2020 Jun 26.},

keywords = {Aged  Atmosphere  Frail Elderly  *Frailty/diagnosis/epidemiology  *Heart Failure/diagnosis/epidemiology  Humans  Prevalence  Stroke Volume  LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Carpometacarpal Dislocation of the Third to Fifth Fingers and an Associated Fracture of the Hamate in a Military Paratrooper},

author = {G Kalinterakis and E Antonogiannakis and A Abdi and G Demetriades and A Koulouktsis and A Syllaios and A Koutras and S Vrouva and A Papagiavis and M Ziogas},

doi = {10.1155/2020/2861604},

issn = {2090-6749 (Print) 

2090-6757},

year  = {2020},

date = {2020-01-01},

journal = {Case Rep Orthop},

volume = {2020},

pages = {2861604},

abstract = {Multiple carpometacarpal dislocations with a simultaneous fracture of the hamate represent less than 1% of all injuries to the hand and wrist regions, with a scarcity of published cases. These injuries usually require a great force, and diagnosis can be missed or delayed because of the high likelihood of other severe concomitant injuries. We report a case of acute closed dislocation of the third through fifth carpometacarpal joints and an associated fracture of the hamate in a military paratrooper. The injury was caused by a wrong landing technique during parachuting. The patient was managed with primary surgical repair, and after a six-month follow-up, he has excellent functional results. The fact that both this clinical entity and the mechanism of injury are very unusual a high index of suspicion is needed, especially for orthopedic surgeons working in military hospitals. Additionally, given that there is a paucity of published cases and optional treatment is controversial, this study corroborates the superiority of surgical repair in a long-term basis.},

note = {2090-6757 

Kalinterakis, Georgios 

Antonogiannakis, Emmanouil 

Abdi, Arezoo 

Demetriades, Georgios 

Koulouktsis, Alexandros 

Syllaios, Athanasios},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Effectiveness and Safety of Complete Decongestive Therapy of Phase I: A Lymphedema Treatment Study in the Greek Population},

author = {E Michopoulos and G Papathanasiou and G Vasilopoulos and M Polikandrioti and E Dimakakos},

doi = {10.7759/cureus.9264},

issn = {2168-8184 (Print) 

2168-8184},

year  = {2020},

date = {2020-01-01},

journal = {Cureus},

volume = {12},

number = {7},

pages = {e9264},

abstract = {Background Lymphedema is a chronic condition caused by a failure in the lymphatic system that most commonly occurs in the limbs. Complete decongestive therapy (CDT) is the gold standard for lymphedema management. Objective To evaluate the effectiveness and safety of complete decongestive therapy (CDT) of phase I in the Greek population with lymphedema. Methods The patients' demographic and clinical characteristics were recorded. CDT was implemented in all patients for 20 sessions in a four-week treatment period. The edema's (excess volume (EV) and percent of excess volume (PEV)) measurements were carried out four times in the treatment period, whereas the percent reduction of excess volume (PREV) was calculated at the end of phase I. Moreover, we recorded every infection, trauma of skin, and pain of limb during the treatment. Results One-hundred five patients with lymphedema were enrolled in the present study, of whom 31.4% had upper limb lymphedema and 68.6% had lower limb lymphedema. All patients with upper limb lymphedema had a secondary type while the corresponding proportion of patients with lower limb lymphedema was 58.3%. A significant reduction (p<0.001) between the pre-treatment and post-treatment values of EV and PEV was found for both upper and lower limb lymphedema. For patients with upper limb lymphedema, the average PREV was 66.5% (interquartile range, 57.3%-80.6%), whereas for patients with lower limb lymphedema, a 71.5% (interquartile range, 64.5%-80.7%) median value was measured. No side effects from the treatment were recorded during CDT. Conclusion The proper treatment of the CDT phase I ensures safety and a great reduction in edema in patients with lymphedema that predispose the success of phase II of CDT.},

note = {2168-8184 

Michopoulos, Emmanouil 

Papathanasiou, George 

Vasilopoulos, Georgios 

Polikandrioti, Maria 

Dimakakos, Evangelos 

Journal Article 

Cureus. 2020 Jul 19;12(7):e9264. doi: 10.7759/cureus.9264.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Psychometric Properties of the 12-Item World Health Organization Disability Assessment Schedule (WHODAS 2.0) in Adult Patients with Motor Disabilities},

author = {M Papadopoulou and S Stasi and D Bakalidou and E Papageorgiou and A Tsokani and T Bratsi and G Papathanasiou},

url = {https://doi.org/10.1007/s10882-019-09721-0},

doi = {10.1007/s10882-019-09721-0},

issn = {1573-3580},

year  = {2020},

date = {2020-01-01},

journal = {Journal of Developmental and Physical Disabilities},

volume = {32},

number = {5},

pages = {801-819},

abstract = {To explore the psychometric properties of the Greek version of the World Health Organization Disability Assessment Schedule (WHODAS 2.0–12 item) in adult patients suffering from motor disabilities. The questionnaire of WHODAS 2.0–12 item was officially translated and cross-culturally adapted into Greek (WHODAS 2.0–12Gr).136 adult patients with motor disabilities included in the present observational study. A reliability study was carried out to explore WHODAS 2.0–12Gr’s internal consistency (Cronbach’s a), repeatability (Pearson’s r) and test retest test-retest reliability between the WHODAS 2.0–12Gr outcomes of day-1 and day-8 [intra-class correlation coefficients with 95% confidence intervals (ICC 95%CI)], and the convergent validity (item-total correlation) of the questionnaire. Exploratory factor analysis (EFA) was used to explore the construct validity of the WHODAS 2.0–12Gr, while the concurrent validity of the questionnaire was testing against the Greek Medical Outcomes Study 36-item Short Form Health Survey version 1.0 (SF-36v1.0-Gr). Reliability properties: WHODAS 2.0–12Gr Cronbach’s a was 0.814 (p < 0.001), Pearson’s r value was 0.980 (p < 0.001) and ICC (95%CI) was 0.990 (0.985–0.993) (p < 0.001). Validity properties: Pearson’s r values of item-total correlation were ranged from 0.376 to 0.736. EFA extracted a 3-factor model. Regarding concurrent validity, the significant correlations between the WHODAS 2.0–12Gr and the SF36v1.0-Gr ranged from −0.169 to −0.720. WHODAS 2.0–12Gr showed significant high to excellent reliability and significant weak to strong validity properties. Overall, it can be suggested that WHODAS 2.0–12Gr could be a reliable and valid tool for assessing patients with motor disabilities.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Reliability and validity of the Greek shoulder pain and disability index in patients with shoulder pain},

author = {A Spanou and I Mamais and D Lamnisos and D Stasinopoulos},

doi = {10.1080/09638288.2018.1519728},

issn = {0963-8288},

year  = {2020},

date = {2020-01-01},

journal = {Disabil Rehabil},

volume = {42},

number = {9},

pages = {1299-1304},

abstract = {Background: The Shoulder Pain and Disability Index is one of the most common questionnaire to evaluate the impact of shoulder disorders on function. There is no valid and reliable Greek version of the Shoulder Pain and Disability Index available at present for all shoulder disorders. Therefore, the aim of the current study was to test the reliability and validity of the Shoulder Pain and Disability Index in patients with shoulder pain for at least four weeks.Methods: The validation study was conducted in clinical settings by questionnaires comprising the Greek Shoulder Pain and Disability Index and Disability of the Arm, Shoulder, and Hand questionnaire. 130 (68 women and 62 men) Greek reading patients over 18 years old with shoulder pain for at least four weeks were recruited from physical therapy clinics. Internal consistency of the translated instrument was measured using Cronbach's α. to establish test-retest reliability, the patients without any change in their condition after 2-3 days from their initial visit were asked to complete the Shoulder Pain and Disability Index for a second time. An intraclass correlation coefficient was used to assess the test-retest reliability of the Shoulder Pain and Disability Index. The Greek version of the Shoulder Pain and Disability Index and Disability of the Arm, Shoulder, and Hand questionnaire was also administered in both visits. Concurrent validity was measured by correlating the Shoulder Pain and Disability Index with the Greek Shoulder Pain and Disability Index and Disability of the Arm, Shoulder and Hand scale using Pearson's correlation coefficient.Results: The results showed that the Greek Shoulder Pain and Disability Index has good internal consistency (Cronbach α = 0.947), test-retest reliability (ICC =0.926) and concurrent validity (r > 0.7). The standard error of measurement (SEM) and the smallest detectable change (SDC) of the Greek SPADI total score were 4.77 and 13.18.Conclusions: The Greek version of the Shoulder Pain and Disability Index is a reliable and valid measure when administered to patients aged over 18 years old with shoulder pain for at least four weeks.Implications for RehabilitationThe Greek version of the Shoulder Pain and Disability Index has been found to be reliable and valid when used in patients with shoulder pain for at least four weeks.The results of the psychometric characteristics were compatible with those of the original English version.The Shoulder Pain and Disability Index could be applied to a Greek-speaking population to assess functional limitations and symptoms in patients over 18 years old with shoulder pain for at least four weeks.},

note = {1464-5165 

Spanou, Alexia 

Mamais, Ioannis 

Lamnisos, Dimitrios 

Stasinopoulos, Dimitrios 

Journal Article 

England 

Disabil Rehabil. 2020 May;42(9):1299-1304. doi: 10.1080/09638288.2018.1519728. Epub 2019 Jan 17.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {International Hip Outcome Tool (12-items) as health-related quality-of-life measure in osteoarthritis: validation of Greek version},

author = {S Stasi and M Stamou and G Papathanasiou and P Frantzeskaki and E Kanavas and G Evaggelou-Sossidis and A Gouskos and A Palantzas and K Poursanidis and G A Macheras},

doi = {10.1186/s41687-020-00207-8},

issn = {2509-8020},

year  = {2020},

date = {2020-01-01},

journal = {J Patient Rep Outcomes},

volume = {4},

number = {1},

pages = {41},

abstract = {BACKGROUND: The 12-item International Hip Outcome Tool (iHOT12) is a patient-reported outcome (PRO) designed to evaluate quality of life. We assessed the psychometric properties of the Greek version (iHOT12-Gr) in hip osteoarthritic patients. METHODS: Data from 124 patients aged > 50 years were used for factor analysis. Reliability evaluation included internal consistency, test-retest reliability, and interpretability. Content validity was examined by calculating the item-level content validity indices (I-CVI) and the scale-level content validity indices (S-CVI), using two methods: S-CVI Average (S-CVI/Ave), and the S-CVI Universal Agreement among experts (S-CVI/UA). Construct validity was tested against Greek versions of the Lower Extremity Functional Scale (LEFS-Greek), Modified Harris Hip Score (MHHS-Gr), and the 30 s chair-to-stand, Timed Up & Go (TUG), and 9-stairs-ascend/descend (9S-A/D) tests. Known-groups validity was examined using LEFS-Greek (cut-off = 53 points) as estimate variable. Responsiveness was examined pre and post total hip arthroplasty (4 and 8 weeks). RESULTS: Factor analysis revealed a two-factor model. Factor-1 (items 1-9) reflects "Symptoms and functionality", while Factor-2 (items 10-12) reflects "Hip disorder-related concerns". Reliability: Internal consistency and test-retest reliability of iHOT12-Gr-total were excellent: Cronbach's alpha > 0.92 and ICC(95% CI) > 0.976(0.96-0.99)(p < 0.001). Interpretability: There was no floor or ceiling effect; measurement error: 3.72 (Factor-1), 3.64 (Factor-2), and 3.22 (iHOT12-Gr-total); minimal detectable change: 10.3 (Factor-1), 10.1 (Factor-2), and 8.92 (iHOT12-Gr-total). VALIDITY: Content validity: The I-CVI value of the 12 items ranged from 1.00 to 0.83, the S-CVI/Ave was 0.97 and the S-CVI/UA was 0.83. Construct validity: iHOT12-Gr correlated strongly with both LEFS-Greek and MHHS-Gr, and weakly but significantly with 30s chair-to-stand, TUG and 9S-A/D (p < 0.001). Known-groups validity showed that iHOT12-Gr well discriminated subgroups of patients (p < 0.001). ROC analysis cut-off points were 51.9 (Factor-1), 25 (Factor-2) and 45.2 (iHOT12-Gr-total) (p < 0.001). Responsiveness: Four and 8 weeks postoperatively, standardized response means of Factor-1, Factor-2, and iHOT12-Gr-total were > 0.8. CONCLUSION: iHOT12-Gr showed excellent reliability properties. The content validity was excellent and significant weak-to-strong correlations were found regarding construct validity. The known-group validity was also significant, while the responsiveness was excellent. iHOT12-Gr could be a reliable and valid PRO for assessing quality of life in patients with hip osteoarthritis.},

note = {2509-8020 

Stasi, Sophia 

Stamou, Magdalini 

Papathanasiou, George 

Frantzeskaki, Paraskevi 

Kanavas, Emmanouil 

Evaggelou-Sossidis, George 

Gouskos, Adamantios 

Palantzas, Andreas 

Poursanidis, Kyriakos 

Macheras, George A 

Journal Article 

J Patient Rep Outcomes. 2020 May 27;4(1):41. doi: 10.1186/s41687-020-00207-8.},

keywords = {LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Similar 2-point discrimination and stereognosia but better locognosia at long term with an independent home-based sensory reeducation program vs no reeducation after low-median nerve transection and repair},

author = {D K Antonopoulos and A F Mavrogenis and P D Megaloikonomos and E Mitsiokapa and G Georgoudis and C T Vottis and G K Antonopoulos and P J Papagelopoulos and S Pneumatikos and S G Spyridonos},

doi = {10.1016/j.jht.2017.10.008},

issn = {0894-1130},

year  = {2019},

date = {2019-01-01},

journal = {J Hand Ther},

volume = {32},

number = {3},

pages = {305-312},

abstract = {STUDY DESIGN: Prospective controlled study. INTRODUCTION: Previous studies evaluated the effectiveness of sensory reeducation (SR) after peripheral nerve injury and repair. However, evidence for long-term clinical usefulness of SR is inconclusive. PURPOSE OF THE STUDY: The purpose of this study is to compare the sensory results of patients with low-median nerve complete transection and microsurgical repair, with and without SR at long term. METHODS: We prospectively studied 52 consecutive patients (mean age, 36 years; range, 20-47 years) with low-median nerve complete transection and microsurgical repair. When reinnervation was considered complete with perception of vibration with a 256-cycles per second tuning fork (mean, 3.5 months after nerve injury and repair), the patients were sequentially allocated (into 2 groups [group SR, 26 patients, SR; group R, 26 patients, reassured on recovery without SR). SR was conducted in a standardized fashion, in 2 stages, as an independent home-based program: the first stage was initiated when reinnervation was considered complete, and included instruction in home exercises to identify familiar objects and papers of different roughness, and localization of light touch (eyes open and closed); the second stage was initiated when the patients experienced normal static and moving 2-point discrimination (2PD) at the index fingertip of injured hand, and included instruction in home exercises for stereognosia, supplementary exercises for localization of light touch, and identification of small objects (eyes open and closed). Exercises were prescribed for 5-10 minutes, 4 times per day. At 1.5, 3, and 6 years after nerve injury and repair, we evaluated the static and moving 2PD, stereognosia with the Moberg's pick-up test, and locognosia with the modified Marsh test. Comparison between groups and time points was done with the nonparametric analysis of variance (Kruskal-Wallis analysis of variance). RESULTS: Static and moving 2PD and stereognosia were not significantly different between groups at any study period. Locognosia was significantly better at 1.5 and 3 years in group SR; locognosia was excellent in 17 patients of group SR vs 5 patients of group R at 1.5-year follow-up and in 14 patients of group SR vs 5 patients of group R at 3-year follow-up. Locognosia was not different between the study groups at 6-year follow-up. CONCLUSION: A 2-stage home program of SR improved locognosia at 1.5 and 3 years after low-median nerve complete transection and repair without significant differences in other modalities or the 6-year follow-up of a small subsample.},

keywords = {Adult, Female Humans, Locognosia, Male Median Nerve/injuries/*surgery, Median nerve, Median Neuropathy/physiopathology/*rehabilitation, Microsurgery, Microsurgical repair, Middle Aged *Physical Therapy, Modalities, PHYSIOLAB, Prospective Studies, Recovery of Function/physiology, Sensation/*physiology, Sensory reeducation, Stereognosia, Stereognosis, Two-point discrimination, Wrist, Young Adult},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {The Beliefs and Attitudes of Cypriot Physical Therapists Regarding the Use of Deep Friction Massage},

author = {A Pitsillides and D Stasinopoulos},

doi = {10.3390/medicina55080472},

issn = {1010-660X (Print) 

1010-660x},

year  = {2019},

date = {2019-01-01},

journal = {Medicina (Kaunas)},

volume = {55},

number = {8},

abstract = {Background: Deep friction massage (DFM) is a widely used technique by physical therapists worldwide for chronic pain management. According to Dr. James Cyriax, compliance with the proposed guidelines is vital to obtain the desired therapeutic results. Objectives: This study explored the beliefs and attitudes of Cypriot physical therapists to DFM and their compliance with the suggested guidelines to identify any empirical-based application patterns and compare them to the suggestions of Cyriax. In addition, the prevalence of DFM use in clinical practice in Cyprus was investigated. Methods: Questionnaires, consisting of 18 multiple choice questions and a table of six sub-questions, were distributed to 90 local physical therapists. Results: A total of 70% of respondents declared that they perform DFM in their daily practice. The respondents answered 11 out of the 19 technical questions in compliance with the guidelines. Conclusion: The study revealed the DFM application pattern of Cypriot physical therapists. The compliance percentage of this pattern to Cyriax guidelines was 58% in general and 62.5% for patients with chronic conditions.},

note = {1648-9144 

Pitsillides, Alexios 

Stasinopoulos, Dimitrios 

Journal Article 

Medicina (Kaunas). 2019 Aug 12;55(8):472. doi: 10.3390/medicina55080472.},

keywords = {Attitudes, Chronic Pain/*therapy  Cyprus  *Friction  *Health Knowledge, Practice  Humans  *Massage  Musculoskeletal Pain/*therapy  *Physical Therapists  Surveys and Questionnaires  LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Cyriax Friction Massage-Suggestions for Improvements},

author = {A Pitsillides and D Stasinopoulos},

doi = {10.3390/medicina55050185},

issn = {1010-660X (Print) 

1010-660x},

year  = {2019},

date = {2019-01-01},

journal = {Medicina (Kaunas)},

volume = {55},

number = {5},

abstract = {Background and objectives: Cyriax friction massage is a widely known and used technique in the field of chronic pain management. Despite its frequent use in daily clinical practice, the technique lacks evidence to support its therapeutic value. While this might be due to various factors, the authors of this paper suggest that the technique might need to be improved and/or modernized according to the recent literature. The purpose of this letter is to further analyze our point of view. Materials and Methods: Using the most relevant methods to the subject literature, the authors intended to point out a few technical details that might need reconsideration and/or modernization. Results: An appropriate terminology is suggested in the text. Further, suggestions are made regarding the technique's interval time, a possible addition of self-treatment, a discussion of the combination with Mill's manipulation, tendon positioning and other parameters. Conclusions: As a therapeutic value has not yet been clearly documented, and since the modernization and/or improvement of the technique might be needed, we suggest that this technique should not be used as a first-line treatment for the management of chronic pain.},

note = {1648-9144 

Pitsillides, Alexios 

Stasinopoulos, Dimitrios 

Journal Article 

Medicina (Kaunas). 2019 May 21;55(5):185. doi: 10.3390/medicina55050185.},

keywords = {Chronic Pain/*therapy  *Friction  Humans  Massage/methods/*standards  Pain Management/methods/standards  LANECASM},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Long term follow-up of quality of life and functional ability in patients with ICU acquired Weakness - A post hoc analysis},

author = {G Sidiras and I Patsaki and E Karatzanos and M Dakoutrou and A Kouvarakos and G Mitsiou and C Routsi and G Stranjalis and S Nanas and V Gerovasili},

doi = {10.1016/j.jcrc.2019.06.022},

issn = {0883-9441},

year  = {2019},

date = {2019-01-01},

journal = {J Crit Care},

volume = {53},

pages = {223-230},

abstract = {PURPOSE: ICU acquired Weakness (ICUaW) is a common complication of critical illness. The aim of our study was the assessment of quality of life (QoL) and functional ability of patients with ICUaW, 6 months post hospital discharge. MATERIAL AND METHODS: Eight hundred seventy eight consecutive patients who had been discharged from the ICU were evaluated and 128 of them, 36 with ICUaW, were eligible for the study. Muscle strength was evaluated with MRC and Hand grip dynamometry. The Functional Independence Measure (FIM) was used to evaluate the functional ability while QoL was assessed with the Nottingham Health Profile and with the SF-36 questionnaire. RESULTS: Patients with ICUaW continued to have low MRC at hospital discharge, [53(49-56) vs. 59(58-60), p < 0.05]. Patients who developed ICUaW had lower Hand grip dynamometry at ICU, hospital discharge and 6 months after (p < 0.05). Patients with ICUaW have significantly lower FIM score at hospital discharge, 3 and 6 months post hospital discharge (p < 0.05) and persistently lower QoL at 3 and 6 months post hospital discharge(p < 0.05). CONCLUSIONS: ICUaW is associated with persistent deficiencies in functional ability and Qol leading to a prolonged period of recovery. Further research is needed in the field of prevention and targeted rehabilitation of functionality in this patient group.},

note = {1557-8615 

Sidiras, Georgios 

Patsaki, Irini 

Karatzanos, Eleftherios 

Dakoutrou, Maria 

Kouvarakos, Alexandros 

Mitsiou, Georgios 

Routsi, Christina 

Stranjalis, Georgios 

Nanas, Serafim 

Gerovasili, Vasiliki 

Journal Article 

Randomized Controlled Trial 

Research Support, Non-U.S. Gov't 

United States 

J Crit Care. 2019 Oct;53:223-230. doi: 10.1016/j.jcrc.2019.06.022. Epub 2019 Jun 21.},

keywords = {Activities of Daily Living  Adolescent  Adult  Aged  Aged},

pubstate = {published},

tppubtype = {article}

}